Browse Tag by LUDE disease
Conditions, Interstitial Cystitis, Overactive Bladder

‘Leaky Bladder’ as the Root of Non-Bacterial Bladder Problems

In my last post I looked at the GAG layer in the bladder and how damage to it can cause problems for the bladder lining, a.k.a the bladder urothelium.

When the bladder urothelium gets damaged it can lose its integrity and become ‘leaky’ or ‘hyper-permeable’. Molecules that shouldn’t normally leave the bladder can get into the space (‘interstitium’ – hence interstitial cystitis) between the layers of the tissue and into the blood.

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